Bronchiectasis was related to the severity of asthma, the presence of chronic expectoration, a previous history of pneumonia, and lower levels of FeNO. ConclusionsĪlmost a third of the patients with uncontrolled moderate-to-severe asthma had bronchiectasis. The NOPES score yielded an AUC-ROC of 70% for the diagnosis of bronchiectasis, with a specificity of 95%. The NOPES score was developed on the basis of these variables (Fe NO, Pneumonia, Expectoration and asthma Severity), and it ranges from 0 to 4 points, where 0 means “no risk” and 4 corresponds to “high risk”. The prevalence of bronchiectasis was 28.4%. ResultsĪ total of 398 patients (60% with severe asthma) were included. A prognostic score was developed using a logistic regression model, which was used to determine the factors associated with bronchiectasis. Diagnosis of bronchiectasis was based on high-resolution computed tomography.
This is a prospective study of data from consecutive patients with uncontrolled moderate-to-severe asthma. The objective of this study was to determine the prevalence of bronchiectasis in uncontrolled moderate-to-severe asthma and to identify risk factors and their correlation with bronchiectasis in these patients. Some studies have reported a high prevalence of bronchiectasis in patients with uncontrolled asthma, but the factors associated with this condition are unknown.
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